Please note that we need about 3 months preparation for the organisation of your in-house training course.
A course about the basics of DOE with practicing of factorial and fractional DOE with a software program (e.g. Minitab 19)
Below is an example of an inhouse training course. This course can be offered as a 2 day or 3 day training.
This course will explain the basics of DOE with practicing with factorial and fractional DOE as well as DOE by RSM and DOE of mixtures of drug ingredients. If you have no or little previous knowledge with DOE, you will learn how to set up an experimental design and how to explore the effect of factors that influence either a development/production process or an analytical method while taking into account interactions between the factors.
DOE and Quality-by-Design
Regulations (EU and FDA)
A factorial experiment
DOE vs One-at-a-Time experiment
Where is DOE applied in development and validation of analytical methods
Where is DOE applied in process development and validation
DOE by hand calculations: effects and interactions
Factorial Experiments (categorical and numeric factors)
Two and three factorial designs
Manual calculation of main effects
Manual calculation of interactions
What is an orthogonal DOE
Exercises with Excel
Acquaintance with Minitab
Basic structure of Minitab software
Input of data
Running a DOE
Plotting output results
Practicing with Minitab
Basic statistical tools for interpretation of DOE output