An expert group of the US Pharmacopoeia (USP) is working on a new chapter on wetting properties of pharmaceutical systems, which may have relevance for both batch and continuous manufacturing. The draft can be found in Pharmaceutical Forum PF49(5).
The expert group proposes a standardisation of analytical technology for the characterisation of wetting properties.
The new general chapter includes the following subchapters:
Background of wetting properties
Applications of wetting properties
Approaches to improve or modify wetting properties
Relevance of the surface tension of liquids for wetting properties
Techniques for measuring the surface tension of liquids
Factors influencing the surface tension of liquids
Evaluation of wetting properties based on the contact angle
Techniques for measuring the contact angle
Factors influencing the contact angle
Relevance of the surface free energy of solids
Techniques for measuring the surface free energy of solids